Инклисиран

Inclisiran

МНН

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

Drugbank

DB14901

АТХ

C10AX16

Фармакологическая группа

Код МКБ 10

E78.0

Категория при беременности по FDA

N (не классифицировано FDA)

CAS

1639324-58-5

Химическое название

duplex of [(2S,4R)-1-{1-[(2-acetamido-2-deoxy-β-Dgalactopyranosyl)oxy]-16,16-bis({3-[(3-{5-[(2-acetamido2-deoxy-β-D-galactopyranosyl)oxy]pentanamido} propyl)amino]-3-oxopropoxy}methyl)-5,11,18-trioxo-14- oxa-6,10,17-triazanonacosan-29-oyl}-4-hydroxypyrrolidin2-yl]methyl hydrogen all-P-ambo-2'-O-methyl-Pthiocytidylyl-(3'→5')-2'-O-methyl-P-thiouridylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'- deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')- 2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-O-methyluridylyl- (3'→5')-thymidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyl-3'-uridylate and all-P-ambo-2'-O-methylP-thioadenylyl-(5'→3')-2'-O-methyl-P-thioadenylyl-(5'→3')- 2'-O-methylguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')- 2'-O-methyluridylyl-(5'→3')-2'-deoxy-2'-fluorocytidylyl- (5'→3')-2'-O-methyluridylyl-(5'→3')-2'-deoxy2'-fluoroguanylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')- 2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methylcytidylyl- (5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')- 2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluorocytidylyl- (5'→3')-2'-O-methylguanylyl-(5'→3')-2'-deoxy2'-fluoroadenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl- (5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methylP-thioadenylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thiocytidylyl- (5'→3')-2'-O-methyladenosine

Химическая формула

C520H679F21N175O309P43S6

Молярная масса

16 248,27 г/моль

Структура

Структура Инклисиран

Иностранные названия

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