Недосиран

Nedosiran

МНН

Rec. INN (наименование, зарегистрированное ВОЗ)

USAN (наименование, принятое к употреблению в США)

АТХ

A16AX25

CAS

2266591-83-5

Химическое название

all-P-ambo-2'-O-methyl-P-thioadenylyl-(3'→5')-2'-O-methyluridylyl- (3'→5')-2'-deoxy-2'-fluoroguanylyl-(3'→5')-2'-O-methyluridylyl- (3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methylguanylyl- (3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl- (3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluorouridylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluoroadenylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-deoxy-2'-fluorocytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-Omethylcytidylyl-(3'→5')-2'-O-methyladenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-{[2-(2-{5-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]pentanamido}ethoxy)ethoxy]methyl}guanylyl-(3'→5')-2'-O-{[2-(2-{5-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]pentanamido}ethoxy)ethoxy]methyl}adenylyl-(3'→5')-2'-O-{[2-(2-{5-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]pentanamido}ethoxy)ethoxy]methyl}adenylyl-(3'→5')-2'-O-{[2-(2-{5-[(2-acetamido-2-deoxy-β-D-galactopyranosyl)oxy]pentanamido}ethoxy)ethoxy]methyl}adenylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methylcytidylyl-(3'→5')-2'-O-methyluridylyl-(3'→5')-2'-O-methylguanylyl-(3'→5')-2'-O-methylcytidine duplex with all-P-ambo-2'-O-methyl-P-thioguanylyl-(5'→3')-2'-O-methyl-P-thioguanylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluorocytidylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methylcytidylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methylguanylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methyladenylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-O-methyluridylyl-(5'→3')-2'-deoxy-2'-fluoroadenylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thioguanylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thioadenylyl-(5'→3')-2'-deoxy-2'-fluoro-P-thiocytidylyl-(5'→3')-methyl hydrogen 2'-O-methyl-5'-oxa-O-5'-carba-5'-uridylate

Химическая формула

C662H865F19N231O413P57S6

Структура

Структура Недосиран

Иностранные названия

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